Budesonide treatment of collagenous colitis: a randomised, double blind, placebo controlled trial with morphometric analysis.

@article{Bonderup2003BudesonideTO,
  title={Budesonide treatment of collagenous colitis: a randomised, double blind, placebo controlled trial with morphometric analysis.},
  author={Ole K Bonderup and Jesper Bach Hansen and Lene Birket-Smith and V Vestergaard and Peter Stubbe Teglbjaerg and Jan Fallingborg},
  journal={Gut},
  year={2003},
  volume={52 2},
  pages={
          248-51
        }
}
BACKGROUND Collagenous colitis is characterised by diarrhoea, lymphocytic inflammation, and a thickened subepithelial collagen layer in the colorectal mucosa. No standard treatment of the disease is established. AIMS To investigate the clinical and histological effect of oral budesonide (Entocort, AstraZeneca) in the treatment of collagenous colitis. PATIENTS Twenty patients with collagenous colitis (collagen layer >10 micro m) and diarrhoea (>4 stools/day and/or stool weight >200 g/day… CONTINUE READING

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