Budesonide reduces neutrophilic but not functional airway response to ozone in mild asthmatics.

@article{Vagaggini2001BudesonideRN,
  title={Budesonide reduces neutrophilic but not functional airway response to ozone in mild asthmatics.},
  author={Barbara Vagaggini and Mauro Taccola and Irene Conti and Stefano Carnevali and Silvana Cianchetti and Maria Laura E Bartoli and Elena Bacci and Federico Lorenzo Dente and Antonella Di Franco and Daniele Giannini and Pier Luigi Paggiaro},
  journal={American journal of respiratory and critical care medicine},
  year={2001},
  volume={164 12},
  pages={2172-6}
}
Ambient ozone concentration is related to asthma exacerbation, but few findings are available regarding the effects of pharmacologic asthma treatment on this relationship. The purpose of this study was to investigate whether inhaled corticosteroids inhibit ozone-induced airway neutrophilic inflammation, as detected in induced sputum, and reduce functional response to ozone exposure. Eleven subjects with mild persistent asthma were exposed for 2 h, on separate days, to 0.27 ppm ozone and to air… CONTINUE READING

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