Budesonide and formoterol inhibit inflammatory mediator production by bronchial epithelial cells infected with rhinovirus.

@article{Skevaki2009BudesonideAF,
  title={Budesonide and formoterol inhibit inflammatory mediator production by bronchial epithelial cells infected with rhinovirus.},
  author={Chrysanthi L Skevaki and Ioannis S Christodoulou and Irini S Spyridaki and Ioanna Tiniakou and Vassiliki Georgiou and Paraskevi Xepapadaki and Dimitrios A. Kafetzis and Nikolaos G. Papadopoulos},
  journal={Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology},
  year={2009},
  volume={39 11},
  pages={1700-10}
}
BACKGROUND Rhinoviruses (RVs) are responsible for the majority of acute asthma and chronic obstructive pulmonary disease (COPD) exacerbations. RVs infect the lower airways and induce the production of pro-inflammatory and remodelling-associated mediators. Budesonide (BUD) and formoterol (FORM) synergize in controlling asthma and COPD exacerbations; however, their effects on virus-induced inflammation and remodelling are less known. OBJECTIVE We investigated whether BUD and FORM synergize in… CONTINUE READING
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