Budding yeast PAK kinases regulate mitotic exit by two different mechanisms

@article{Chiroli2003BuddingYP,
  title={Budding yeast PAK kinases regulate mitotic exit by two different mechanisms},
  author={Elena Chiroli and Roberta Fraschini and Alessia Beretta and Mariagrazia Tonelli and G. Lucchini and Simonetta Piatti},
  journal={The Journal of Cell Biology},
  year={2003},
  volume={160},
  pages={857 - 874}
}
We report the characterization of the dominant-negative CLA4t allele of the budding yeast CLA4 gene, encoding a member of the p21-activated kinase (PAK) family of protein kinases, which, together with its homologue STE20, plays an essential role in promoting budding and cytokinesis. Overproduction of the Cla4t protein likely inhibits both endogenous Cla4 and Ste20 and causes a delay in the onset of anaphase that correlates with inactivation of Cdc20/anaphase-promoting complex (APC)-dependent… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 77 references

Cdc28 Activates Exit from Mitosis in Budding Yeast

The Journal of cell biology • 2000
View 9 Excerpts
Highly Influenced

A role for cell polarity proteins in mitotic exit.

The EMBO journal • 2002
View 14 Excerpts
Highly Influenced

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