Buccal swabs and treated cards: methodological considerations for molecular epidemiologic studies examining pediatric populations.

@article{Beckett2008BuccalSA,
  title={Buccal swabs and treated cards: methodological considerations for molecular epidemiologic studies examining pediatric populations.},
  author={Sara M Beckett and Stephen J Laughton and Luciano Dalla Pozza and Geoffrey B. McCowage and Glenn M. Marshall and Richard Julian Cohn and Elizabeth Milne and Lesley Jayne Ashton},
  journal={American journal of epidemiology},
  year={2008},
  volume={167 10},
  pages={1260-7}
}
Self-collection of buccal cells provides a noninvasive method for obtaining biologic samples for genetic analyses in pediatric studies. Nevertheless, low yields, microbial contamination, and degradation of buccal samples present challenges for epidemiologic studies incorporating genetic investigations. The aims of this study were to compare the quality and yield of DNA extracted from buccal specimens with BuccalAmp swabs (Epicenter BioTechnologies, Madison, Wisconsin) or FTA cards (Whatman, Inc… CONTINUE READING

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