Bubble Formation in Physical and Biological Systems: A Manifestation of Counterdiffusion in Composite Media

@article{Graves1973BubbleFI,
  title={Bubble Formation in Physical and Biological Systems: A Manifestation of Counterdiffusion in Composite Media},
  author={David J. Graves and J Idicula and C. J. Lambertsen and John Anthony Quinn},
  journal={Science},
  year={1973},
  volume={179},
  pages={582 - 584}
}
The counterdiffusion of gases across a composite layer can lead to supersaturation and development of bubbles within the layer. A physicochemical model has been derived to predict the extent of such supersaturation; experiments with inert liquid layers confirm predictions. These findings explain the evolution of cutaneous lesions observed in man during simulated deep-sea dives and the cutaneous lesions and intravascular bubbles experimentally induced in pigs by exchanging certain inert gases… 

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