Brucella intracellular replication requires trafficking through the late endosomal/lysosomal compartment.


Upon entry into mammalian cells, the intracellular pathogen Brucella abortus resides within a membrane-bound compartment, the Brucella-containing vacuole (BCV), the maturation of which is controlled by the bacterium to generate a replicative organelle derived from the endoplasmic reticulum (ER). Prior to reaching the ER, Brucella is believed to ensure its… (More)
DOI: 10.1111/j.1600-0854.2008.00718.x


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