• DOI:10.1172/JCI62308
Corpus ID: 24434742

Brown adipose tissue regulates glucose homeostasis and insulin sensitivity.

@article{Stanford2013BrownAT,
  title={Brown adipose tissue regulates glucose homeostasis and insulin sensitivity.},
  author={K. Stanford and R. J. Middelbeek and K. Townsend and D. An and E. B. Nygaard and Kristen M. Hitchcox and Kathleen R Markan and Kazuhiro Nakano and M. Hirshman and Y. Tseng and L. Goodyear},
  journal={The Journal of clinical investigation},
  year={2013},
  volume={123 1},
  pages={
          215-23
        }
}

• K. Stanford, R. J. Middelbeek, +8 authors L. Goodyear
• Published 2013
• Biology, Medicine
• The Journal of clinical investigation

Brown adipose tissue (BAT) is known to function in the dissipation of chemical energy in response to cold or excess feeding, and also has the capacity to modulate energy balance. To test the hypothesis that BAT is fundamental to the regulation of glucose homeostasis, we transplanted BAT from male donor mice into the visceral cavity of age- and sex-matched recipient mice. By 8-12 weeks following transplantation, recipient mice had improved glucose tolerance, increased insulin sensitivity, lower… Expand

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