Brown adipose tissue and thermogenesis

  title={Brown adipose tissue and thermogenesis},
  author={Anna Fenzl and Florian W. Kiefer},
  journal={Hormone Molecular Biology and Clinical Investigation},
  pages={25 - 37}
  • A. FenzlF. Kiefer
  • Published 1 July 2014
  • Biology
  • Hormone Molecular Biology and Clinical Investigation
Abstract The growing understanding of adipose tissue as an important endocrine organ with multiple metabolic functions has directed the attention to the (patho)physiology of distinct fat depots. Brown adipose tissue (BAT), in contrast to bona fide white fat, can dissipate significant amounts of chemical energy through uncoupled respiration and heat production (thermogenesis). This process is mediated by the major thermogenic factor uncoupling protein-1 and can be activated by certain stimuli… 

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