Brown-Séquard: Selected Contributions of a Nineteenth-Century Neuroscientist

  title={Brown-S{\'e}quard: Selected Contributions of a Nineteenth-Century Neuroscientist},
  author={Michael J. Aminoff},
  journal={The Neuroscientist},
  pages={60 - 65}
  • M. Aminoff
  • Published 1 February 2000
  • Psychology
  • The Neuroscientist
That eccentric experimentalist, Charles Edouard Brown-Séquard, flitted restlessly between the major cities of the old and new worlds in the nineteenth century, replacing outdated concepts with new ideas of his own concerning the operation of the nervous system in health and disease. He used the experimental approach to generate hypotheses but had no interest in showing by meticulous study that his views were correct, leaving this to others. Extending his work on the integrative action of the… 

Figures from this paper

Brown-Séquard, a restless mind.
Brown-Séquard, a remarkable medical personality of the 19 th century, was born in a small island of the Indian Ocean and is considered by some as the "father" of endocrinology, due to his studies on glands and their secretions.
Brown-Séquard: On neural networks and brain localization of functions
The notion that the brain (encephalon) is a network of interconnected neurons has a long and memorable history. Cytoarchitectonic and hodological studies coupled with advanced neuroimaging techniques
Chapter 40: history of neurology in France.
Brown-Séquard, um pesquisador itinerante - De uma pequena ilha do Oceano Índico para o mundo Brown-Séquard, a wandering researcher - From a small island of the Indian Ocean to the world
Brown-Sequard, researcher and physician, was one of the most amazing personality of the 19 th century, who travelled over the world exerting his skills of a reputable physician and an innovative experimental and clinical researcher.
The role of testosterone in sexuality and paraphilia--a neurobiological approach. Part II: testosterone and paraphilia.
From a neurobiological perspective an extended scientific proposal for design features to investigate the effects of antiandrogen treatment in large clinical trials is presented.
Elementos para uma história da neuroascese
O espetacular progresso das neurociencias e o intenso processo de popularizacao, via midia, de imagens e informacoes que associam a atividade cerebral a praticamente todos os aspectos da vida


Charles Édouard Brown‐Séquard
Brown-Séquard's career as Harvard's first professor of the physiology and pathology of the nervous system is chronicled in a unique and previously unpublished series of his private letters and
Results of Hemisection of the Spinal Cord in Monkeys. [Abstract]
While engaged in studying experimentally the connections of the cells of Clarke’s column with the ascending tracts of the spinal cord in the Monkey, I was surprised to find that after hemisection in
Organotherapy, British physiology, and discovery of the internal secretions
  • M. Borell
  • Psychology
    Journal of the history of biology
  • 1976
In April 1891, the French physiologist and neurologist C.-E. BrownSequard (1817-1894) and his assistant Arsene d'Arsonval (1851-1940) suggested to the Society of Biology at Paris that potent
Plasticity of plasticity? Changes in the pattern of perceptual correlates of reorganization after amputation.
While the overall extent of reorganization is a rather stable phenomenon, the concomitant changes in the pattern of sensory processing are not, and this may be due to the fact that alterations of sensoryprocessing are not hardwired, but are rather mediated by an extensive and interconnected neural network with fluctuating synaptic strengths.
Plasticity of primary somatosensory cortex paralleling sensorimotor skill recovery from stroke in adult monkeys.
Adult owl and squirrel monkeys were trained to master a small-object retrieval sensorimotor skill and revealed a postlesion reemergence of the representation of the fingertips engaged in the behavior in novel locations in two of five monkeys and a less substantial change in the representation in the hand in the intact parts of area 3b in three ofFive monkeys.
Neural organization and plasticity of language
Rapid plasticity of human cortical movement representation induced by practice.
Training rapidly, and transiently, established a change in the cortical network representing the thumb, which encoded kinematic details of the practiced movement, suggesting that this phenomenon may be regarded as a short-term memory for movement and be the first step of skill acquisition.
Cortical plasticity: from synapses to maps.
The goal of the current paper is to review the fields of both synaptic and cortical map plasticity with an emphasis on the work that attempts to unite both fields, to highlight the gaps in the understanding of synaptic and cellular mechanisms underlying cortical representational plasticity.
Note on the Treatment of Myxœdema by Hypodermic Injections of an Extract of the Thyroid Gland of a Sheep
It was decided that to avoid rupture of the uterus the fcetus must be speedily removed, and total extirpation was preferable to (esarean section or Porro's operation), as the disease was limited to the uterus and did not encroach on the vagina.