Broussoflavonol B restricts growth of ER-negative breast cancer stem-like cells.

@article{Guo2013BroussoflavonolBR,
  title={Broussoflavonol B restricts growth of ER-negative breast cancer stem-like cells.},
  author={Mingxi Guo and Molin Wang and Xintian Zhang and Hao Deng and Zhaoyi Wang},
  journal={Anticancer research},
  year={2013},
  volume={33 5},
  pages={1873-9}
}
Accumulating experimental and clinical evidence has indicated that tumor-initiating or cancer stem-like cells are a sub-population of tumor cells capable of initiating and driving tumor growth, and cancer stem-like cells are resistant to most current cancer therapies, including chemo- and radiation therapy. More effective targeted-therapeutic approaches are urgently needed to eliminate cancer stem-like cells. Here, we report that broussoflavonol B, a chemical purified from the bark of the Paper… CONTINUE READING