Bronchoprotection by salmeterol: cell stabilization or functional antagonism? Comparative effects on histamine- and AMP-induced bronchoconstriction.

@article{Soler1994BronchoprotectionBS,
  title={Bronchoprotection by salmeterol: cell stabilization or functional antagonism? Comparative effects on histamine- and AMP-induced bronchoconstriction.},
  author={M A Gonz{\'a}lez Soler and Ladina Joos and Chris Thomas Bolliger and Serge Elsasser and Andr{\'e} Paul Perruchoud},
  journal={The European respiratory journal},
  year={1994},
  volume={7 11},
  pages={1973-7}
}
Salmeterol provides bronchoprotection against a number of constrictor stimuli for more than 12 h after a single dose. This effect could be due either to functional antagonism at the level of airway smooth muscle or to cell-stabilizing effects of the compound. In this study, we attempted to clarify this mechanism by comparing the effects of salmeterol (50… CONTINUE READING