Bronchodilator subsensitivity after chronic dosing with eformoterol in patients with asthma.

@article{Newnham1994BronchodilatorSA,
  title={Bronchodilator subsensitivity after chronic dosing with eformoterol in patients with asthma.},
  author={Denise Newnham and D. G. Mcdevitt and Brian J Lipworth},
  journal={The American journal of medicine},
  year={1994},
  volume={97 1},
  pages={
          29-37
        }
}
PURPOSE The aim of the present study was to evaluate in vivo and in vitro beta 2-adrenoceptor responsiveness after chronic inhaled therapy with the long-acting beta 2-agonist eformoterol or placebo, given twice daily, in patients with mild to moderate asthma. PATIENTS AND METHODS Seven asthmatic patients, age 34 +/- 5 years were evaluated. Mean forced expiratory volume in 1 second (FEV1) (% predicted) at entry was 58 +/- 5%. After at least 2 weeks run-in without beta 2-agonist therapy… CONTINUE READING
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