Bronchodilator reversibility in COPD: the roguish but harmless little brother of airway hyperresponsiveness?

A irway hyperresponsiveness (AHR) in chronic obstructive pulmonary disease (COPD) is well described in an epidemiological context with rather consistent results. It is known that AHR is a negative prognostic marker, associated with an accelerated decline in forced expiratory volume in one second (FEV1) [1–3] and probably also associated with an increase in… CONTINUE READING