Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease.

@article{Albert2012BronchodilatorRA,
  title={Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease.},
  author={Paul S Albert and A Agusti and Lisa D. Edwards and Ruth Tal-Singer and Julie Carol Yates and Per S. Bakke and Bartolome R Celli and Harvey O Coxson and Courtney C Crim and David A. Lomas and W. MacNee and Bruce E. Miller and Stephen I. Rennard and Edwin K. Silverman and Joergen Vestbo and Emiel F. M. Wouters and Peter M. A. Calverley},
  journal={Thorax},
  year={2012},
  volume={67 8},
  pages={701-8}
}
BACKGROUND Bronchodilator responsiveness is a potential phenotypic characteristic of chronic obstructive pulmonary disease (COPD). We studied whether change in lung function after a bronchodilator is abnormal in COPD, whether stable responder subgroups can be identified, and whether these subgroups experience different clinical outcomes. METHODS 1831 patients with COPD, 285 smoking (SC) and 228 non-smoking (NSC) controls from the Evaluation of COPD Longitudinally to Identify Predictive… CONTINUE READING
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