Bronchoconstriction and airway biology: potential impact and therapeutic opportunities.


Recent work has demonstrated that mechanical forces occurring in the airway as a consequence of bronchoconstriction are sufficient to not only induce symptoms but also influence airway biology. Animal and human in vitro and in vivo work demonstrates that the airways are structurally and functionally altered by mechanical stress induced by… (More)
DOI: 10.1378/chest.14-1142


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