Bronchoalveolar mast cells in extrinsic asthma: a mechanism for the initiation of antigen specific bronchoconstriction.

@article{Flint1985BronchoalveolarMC,
  title={Bronchoalveolar mast cells in extrinsic asthma: a mechanism for the initiation of antigen specific bronchoconstriction.},
  author={K. Flint and K. Leung and B. Hudspith and J. Brostoff and F. Pearce and N. Johnson},
  journal={British Medical Journal (Clinical research ed.)},
  year={1985},
  volume={291},
  pages={923 - 926}
}
Bronchoalveolar lavage performed in 10 patients with extrinsic asthma and 14 controls yielded similar recoveries of fluid and cells. Mast cells and eosinophils, however, formed a greater proportion of the cells recovered from the asthmatic subjects (p less than 0.001 for mast cells; p less than 0.01 for eosinophils), the histamine content of the lavage cells being correspondingly increased (p less than 0.01). Both the percentage of mast cells and the histamine content of lavage cells were… Expand
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