Bronchiolitis obliterans. A new clinical-pathologic complication of irradiation pneumonitis.

@article{Kaufman1990BronchiolitisOA,
  title={Bronchiolitis obliterans. A new clinical-pathologic complication of irradiation pneumonitis.},
  author={Jacqueline N Kaufman and Renee Komorowski},
  journal={Chest},
  year={1990},
  volume={97 5},
  pages={
          1243-4
        }
}
A patient underwent chest irradiation for small-cell carcinoma of the left lung. Several weeks following cessation of irradiation, the patient developed hypoxemia and reticulonodular densities within the radiation port. Open lung biopsy yielded a pathologic diagnosis consistent with irradiation pneumonitis along with a previously unreported association, bronchiolitis obliterans. Bronchiolitis obliterans should be included in the pathologic description of irradiation pneumonitis. 

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Supported by grant 30219886.5, CNPq. tProfessor of Medicine; Head, Pulmonary Function Laboratory. §Associate Professor

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