Bronchiolitis obliterans syndrome 2001: an update of the diagnostic criteria.

  title={Bronchiolitis obliterans syndrome 2001: an update of the diagnostic criteria.},
  author={Marc Estenne and Janet R Maurer and Annette Boehler and James J Egan and Adaani Frost and Marshall Hertz and George B. Mallory and Gregory Ian Snell and Samuel A. Yousem},
  journal={The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation},
  volume={21 3},
Bronchiolitis obliterans (BO) is a major cause of allograft dysfunction in lung and heart lung transplant recipients. Clinically, progressive airflow limitation develops because of small airway obstruction. The disease has a variable course. Some patients experience rapid loss of lung function and respiratory failure. Others experience either slow progression or intermittent loss of function with long plateaus during which pulmonary function is stable. Histologic confirmation is difficult… CONTINUE READING
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