Bronchiectasis

@article{Chalmers2018Bronchiectasis,
  title={Bronchiectasis},
  author={J. Chalmers and A. Chang and S. Chotirmall and R. Dhar and P. McShane},
  journal={Nature Reviews Disease Primers},
  year={2018},
  volume={4},
  pages={1-18}
}
Bronchiectasis refers to abnormal dilatation of the bronchi. Airway dilatation can lead to failure of mucus clearance and increased risk of infection. Pathophysiological mechanisms of bronchiectasis include persistent bacterial infections, dysregulated immune responses, impaired mucociliary clearance and airway obstruction. These mechanisms can interact and self-perpetuate, leading over time to impaired lung function. Patients commonly present with productive cough and recurrent chest… Expand