Bronchial subepithelial fibrosis correlates with airway responsiveness to methacholine.

  title={Bronchial subepithelial fibrosis correlates with airway responsiveness to methacholine.},
  author={Louis-Philippe Boulet and Michel Laviolette and H{\'e}l{\`e}ne Turcotte and A Pierre Cartier and Martin Dugas and J. L. Malo and Michel Boutet},
  volume={112 1},
OBJECTIVES To evaluate the relationships between airway subepithelial collagen deposition and epithelial desquamation with airflow obstruction and hyperresponsiveness in different types of asthma and other respiratory conditions such as chronic cough and allergic rhinitis. DESIGN AND PARTICIPANTS We compared the histopathologic features observed on bronchial biopsy specimens obtained from 80 subjects: 38 with different types of asthma, 19 with chronic cough, 13 with allergic rhinitis, and 10… CONTINUE READING
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