Bronchial branching correlates with specific glycosidase activity, extracellular glycosaminoglycan accumulation, TGF beta(2), and IL-1 localization during chick embryo lung development.

@article{Calvitti2004BronchialBC,
  title={Bronchial branching correlates with specific glycosidase activity, extracellular glycosaminoglycan accumulation, TGF beta(2), and IL-1 localization during chick embryo lung development.},
  author={Mario Calvitti and Tiziano Baroni and Carla Calastrini and Cinzia Lilli and Elisabetta Caramelli and Ennio Becchetti and Paolo Carinci and Laura Vizzotto and Giordano Stabellini},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={2004},
  volume={52 3},
  pages={325-34}
}
During organ differentiation, cell-extracellular matrix (ECM) interactions are required. The components of the ECM, such as glycosaminoglycans, fibronectin, laminin, and collagens, change in relation to cytokine and enzyme activity. Moreover, glycosaminoglycans (GAGs) are components of the ECM that play an important role in both cytokine regulation and cell activities. In this work we studied the accumulation of hyaluronic acid and chondroitin sulfate and heparan sulfate proteoglycans (PGs… CONTINUE READING