Bromopropylate: induction of hepatic cytochromes P450 and absence of covalent binding to DNA in mouse liver.

@article{Thomas1994BromopropylateIO,
  title={Bromopropylate: induction of hepatic cytochromes P450 and absence of covalent binding to DNA in mouse liver.},
  author={Henrik Thomas and Peter Sagelsdorff and Elvira Molitor and T Skripsky and Felix Waechter},
  journal={Toxicology and applied pharmacology},
  year={1994},
  volume={129 1},
  pages={155-62}
}
Oral administration of benzilic acid ester-based acaricide bromopropylate at daily doses of 3, 15, 100, and 300 mg/kg body wt to young adult male Tif:MAGf mice for 14 days caused slightly increased liver weights in the high-dose group. A dose-dependent increase of the microsomal cytochrome P450 content was accompanied by elevated ethoxycoumarin O-deethylase… CONTINUE READING