Bromohydrin pyrophosphate enhances antibody-dependent cell-mediated cytotoxicity induced by therapeutic antibodies.

Abstract

In human blood, 1% to 5% of lymphocytes are gammadelta T cells; they mostly express the gammadelta T-cell receptor (TCR)Vgamma9, recognize nonpeptide phosphoantigens (PAgs) produced by microbes and tumor cells, and mediate different modes of lytic activities directed against tumor target cells. Antibody-dependent cell-mediated cytotoxicity (ADCC) mediated… (More)
DOI: 10.1182/blood-2008-08-172296

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@article{GertnerDardenne2009BromohydrinPE, title={Bromohydrin pyrophosphate enhances antibody-dependent cell-mediated cytotoxicity induced by therapeutic antibodies.}, author={Julie Gertner-Dardenne and C ecile Bonnafous and Christine Bezombes and Aude-Helene Capietto and Virginie Scaglione and Sophie Ingoure and Delphine Cendron and Emilie T E Gross and Jean-François Lepage and Anne Quillet-Mary and Lo{\"i}c Ysebaert and Guy Laurent and H{\'e}l{\`e}ne Sicard and Jean-Jacques Fourni{\'e}}, journal={Blood}, year={2009}, volume={113 20}, pages={4875-84} }