Bromocriptine treatment over 12 years in acromegaly: effect on growth hormone and prolactin secretion.

@article{Rau1992BromocriptineTO,
  title={Bromocriptine treatment over 12 years in acromegaly: effect on growth hormone and prolactin secretion.},
  author={H C Rau and Peter H. Althoff and Kathrin Schmidt and Klaus Henning Usadel},
  journal={Acta endocrinologica},
  year={1992},
  volume={126 3},
  pages={247-52}
}
It is not known whether bromocriptine treatment in acromegaly can be implemented for a life-long period. To elucidate this problem, the secretory GH and PRL states of 12 patients with acromegaly were determined, before bromocriptine treatment, under therapy (15.0 +/- 6.8 mg/day for 12 +/- 3 years; mean +/- SD) and during two-weeks long drug withdrawal after long-term treatment, respectively. Before therapy, all patients showed a non-sufficient GH suppression after oral glucose load (greater… CONTINUE READING