Broader autism phenotype: evidence from a family history study of multiple-incidence autism families.

@article{Piven1997BroaderAP,
  title={Broader autism phenotype: evidence from a family history study of multiple-incidence autism families.},
  author={J. Piven and P. Palmer and D. Jacobi and D. Childress and Stephan Arndt},
  journal={The American journal of psychiatry},
  year={1997},
  volume={154 2},
  pages={
          185-90
        }
}
OBJECTIVE Studies of families ascertained through a single autistic proband suggest that the genetic liability for autism may be expressed in nonautistic relatives in a phenotype that is milder but qualitatively similar to the defining features of autism. The objective of this study was to examine behaviors that may define this broader phenotype in relatives ascertained through two autistic siblings. METHOD The authors used a semistructured family history interview to compare the rates of… Expand
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