Broadband proton decoupling in human 31P NMR spectroscopy.

  title={Broadband proton decoupling in human 31P NMR spectroscopy.},
  author={P R Luyten and G Bruntink and F M Sloff and J. W. B. Vermeulen and J.M.M. van der Heijden and Jan A den Hollander and Arend Heerschap},
  journal={NMR in biomedicine},
  volume={1 4},
The limited chemical shift dispersion of in vivo 31P NMR spectra obtained at the relatively low field strengths used for human applications is the cause of poor spectral resolution. This makes it difficult to obtain accurate quantitative information from overlapping resonances, and interesting resonances may be obscured. At 1.5 T unresolved 1H-31P couplings contribute significantly to the linewidth of in vivo 31P NMR resonances. Therefore, proton decoupling can improve spectral resolution… CONTINUE READING
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