Broad heparin-binding haemagglutinin-specific cytokine and chemokine response in infants following Mycobacterium bovis BCG vaccination.

@article{Smith2012BroadHH,
  title={Broad heparin-binding haemagglutinin-specific cytokine and chemokine response in infants following Mycobacterium bovis BCG vaccination.},
  author={Steven G. Smith and Sophie Lecher and Rose Blitz and Camille Locht and Hazel M Dockrell},
  journal={European journal of immunology},
  year={2012},
  volume={42 9},
  pages={
          2511-22
        }
}
Heparin-binding haemagglutinin (HBHA)-specific immune responses have been linked to protection against tuberculosis (TB). We investigated the hypothesis that BCG vaccination of human infants primes an HBHA-specific response, using multiplex to measure secreted cytokines and chemokines following HBHA and Mycobacterium tuberculosis purified protein derivative (PPD) stimulation of diluted whole blood samples from BCG-vaccinated or -unvaccinated infants. Of 42 analytes measured, 24 and 32… CONTINUE READING
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Tuberculosis in London 2009: annual report on tuberculosis surveillance in London

  • C. Anderson, H. Maguire, S. Anderson, J. Carless, L. Kanfoudi
  • Health Protection Agency London Regional…
  • 2011

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