Broad chromosomal domains of histone modification patterns in C. elegans.

  title={Broad chromosomal domains of histone modification patterns in C. elegans.},
  author={Tao Liu and Andreas Rechtsteiner and Thea A. Egelhofer and Anne Vielle and Isabel J Latorre and M Cheung and Sevinc Ercan and Kohta Ikegami and Morten Jensen and Paulina Kolasinska-Zwierz and Heidi Rosenbaum and Hyunjin Shin and Scott Taing and Teruaki Takasaki and A. Leonardo Iniguez and Arshad Desai and Abby F. Dernburg and Hiroshi Kimura and Jason D. Lieb and Julie Ahringer and Susan Strome and X. Shirley Liu},
  journal={Genome research},
  volume={21 2},
Chromatin immunoprecipitation identifies specific interactions between genomic DNA and proteins, advancing our understanding of gene-level and chromosome-level regulation. Based on chromatin immunoprecipitation experiments using validated antibodies, we define the genome-wide distributions of 19 histone modifications, one histone variant, and eight chromatin-associated proteins in Caenorhabditis elegans embryos and L3 larvae. Cluster analysis identified five groups of chromatin marks with… CONTINUE READING
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