Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target.

Abstract

Broadly neutralizing antibodies (bNAbs), which develop over time in some HIV-1-infected individuals, define critical epitopes for HIV vaccine design. Using a systematic approach, we have examined neutralization breadth in the sera of about 1800 HIV-1-infected individuals, primarily infected with non-clade B viruses, and have selected donors for monoclonal… (More)
DOI: 10.1126/science.1178746

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