Brn-5 is a divergent POU domain factor highly expressed in layer IV of the neocortex.

@article{Andersen1993Brn5IA,
  title={Brn-5 is a divergent POU domain factor highly expressed in layer IV of the neocortex.},
  author={Bogi Andersen and Marcus D. Schonemann and Richard V. Pearse and Keith J. Jenn{\'e} and Jeffrey S Sugarman and Michael G. Rosenfeld},
  journal={The Journal of biological chemistry},
  year={1993},
  volume={268 31},
  pages={
          23390-8
        }
}
We have identified rat cDNA clones that encode a POU domain protein, referred to as brain-5 (Brn-5). During embryogenesis in the rat, Brn-5 is widely expressed with highest levels in the developing brain and spinal cord from embryonic day 12.5. In the adult, Brn-5 mRNA is most abundant in the brain, where it is diffusely expressed with the exception of an enrichment in layer IV of the neocortex. However, Brn-5 is also found in multiple adult tissues outside the central nervous system, including… CONTINUE READING

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