British Society for Allergy and Clinical Immunology guidelines for the management of egg allergy

  title={British Society for Allergy and Clinical Immunology guidelines for the management of egg allergy},
  author={Andrew T. Clark and Isabel J. Skypala and Susan C. Leech and Pamela W. Ewan and Pierre Dugu{\'e} and Nicola Brathwaite and P A J Huber and Shuaib Nasser},
  journal={Clinical \& Experimental Allergy},
This guideline advises on the management of patients with egg allergy. Most commonly, egg allergy presents in infancy, with a prevalence of approximately 2% in children and 0.1% in adults. A clear clinical history and the detection of egg white‐specific IgE (by skin prick test or serum assay) will confirm the diagnosis in most cases. Egg avoidance advice is the cornerstone of management. Egg allergy often resolves and re‐introduction can be achieved at home if reactions have been mild and there… 

BSACI 2021 guideline for the management of egg allergy

  • S. LeechP. Ewan A. Clark
  • Medicine
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
  • 2021
This guideline was prepared by the Standards of Care Committee (SOCC) of the British Society for Allergy and Clinical Immunology (BSACI) and is intended for allergists and others with a special interest in allergy.

Position document: IgE-mediated allergy to egg protein.

Molecular diagnosis of egg allergy

Using recombinant allergens, IgE-binding epitopes, and microarrays, molecular-based technologies show promising results, however, none of these tests is ready to be used in clinical practice and oral food challenge remains the standard for the diagnosis of egg allergy.

MMR and egg allergy: to vaccinate or not to vaccinate?

  • S. BandiC. Macdougall
  • Medicine
    The British journal of general practice : the journal of the Royal College of General Practitioners
  • 2010
In spite of various recommendations and guidelines, children are still being referred for MMR to be administered in a hospital setting and it is believed that inclusion of these recommendations in all the immunisation leaflets and related websites would lead to increased awareness and reduce the confusion surrounding this controversy.

Measles, mumps, and rubella vaccination in a child with suspected egg allergy

A mother presents with her 12 month old son requesting testing for an egg allergy before the measles, mumps, and rubella (MMR) vaccination; his older sister has a severe egg allergy. Understanding

The Evaluation of Allergic Reaction in Patients with Egg Allergy After Measles-Mumps-Rubella Vaccination

MMR vaccine can be administered as single dose without skin test to patients with egg allergy, especially patients who have atopic dermatitis, however, intervention equipment for possible allergic reaction should be available in center where the vaccines are applicated.

Egg allergy in children under the age of 5 years

This article will look at how egg allergy can be managed through dietary avoidance, with a focus on infants and young children.

Immunization practices in children with a history of allergies

Egg allergy was the most common barrier of vaccine administration in children referred from family physicians, and the administration of the measles-mumps-rubella vaccine in primary care settings to prevent delays in national vaccine schedule is supported.

Diagnosis and assessment of food allergy in children and young people in primary care and community settings: NICE clinical guideline.

  • J. WalshN. O’Flynn
  • Medicine
    The British journal of general practice : the journal of the Royal College of General Practitioners
  • 2011
A guideline on the symptoms that should prompt consideration of food allergy when a child or young person presents in primary or community care is developed, which covers children and young people with food intolerances, reactions to pharmacological agents, or reactions to those substances that naturally occur in foods.

[Allergy to egg proteins in children].

The identification and elimination of egg proteins from the diet is the primary treatment and the only one validated to this food, but there are more studies needed to stablish protocols for each specific egg allergen before the oral inmunotherapy becomes a routine practice.



The natural history of egg allergy.

Egg allergy in infancy predicts respiratory allergic disease by 4 years of age

Egg allergy in infancy, especially when coexisting with eczema, increases respiratory allergic symptoms and aero‐allergen sensitization in early childhood.

Safe administration of influenza vaccine to patients with egg allergy.

The management of anaphylaxis in childhood: position paper of the European academy of allergology and clinical immunology

Practical guidelines for managing anaphylaxis in childhood based on the limited evidence available are provided and the creation of national and European databases are expected to generate better‐quality data and help develop a stepwise approach for a better management of paediatric anAPHylaxis.

Correlation between specific immunoglobulin E levels and the severity of reactions in egg allergic patients

  • A. H. BenhamouS. ZamoraP. Eigenmann
  • Medicine, Biology
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology
  • 2008
The results show a correlation between IgE titres and the severity of the clinical reaction to egg, which may help to determine the potential risk of a reaction to eggs.

Threshold levels in food challenge and specific IgE in patients with egg allergy: is there a relationship?

The purpose of this study was to determine the utility of specific IgE in estimating threshold level to predict a positive outcome in food challenge and found no significant relationship between thespecific IgE concentration (egg white) and the challenge threshold level.

Natural course of sensitization to hen's egg in children not previously exposed to egg ingestion.

In children sensitized to egg without previous ingestion of that food, egg tolerance appears probably in some by the age of 3 but may reveal much more prolonged in a limited number.

The safety of egg-containing vaccines for egg-allergic patients.

Utility of food-specific IgE concentrations in predicting symptomatic food allergy.

  • H. Sampson
  • Medicine
    The Journal of allergy and clinical immunology
  • 2001
Quantification of food-specific IgE is a useful test for diagnosing symptomatic allergy to egg, milk, peanut, and fish in the pediatric population and could eliminate the need to perform double-blind, placebo-controlled food challenges in a significant number of children.

Atopy patch tests, together with determination of specific IgE levels, reduce the need for oral food challenges in children with atopic dermatitis.

The combination of positive APT results and measurement of levels of specific IgE makes double-blind, placebo-controlled, food challenges superfluous for suspected CM and HE allergy.