Bright sub-20-nm cathodoluminescent nanoprobes for electron microscopy

@article{Prigozhin2019BrightSC,
  title={Bright sub-20-nm cathodoluminescent nanoprobes for electron microscopy},
  author={Maxim B. Prigozhin and Peter C. Maurer and Alexandra M Courtis and Nian Liu and Michael D. Wisser and Chris Siefe and Bining Tian and Emory M. Chan and Guosheng Song and Stefan Fischer and Shaul Aloni and D. Frank Ogletree and Edward S. Barnard and Lydia-Marie Joubert and Jianghong Rao and A. Paul Alivisatos and Roger M. Macfarlane and Bruce E. Cohen and Yi Cui and Jennifer A. Dionne and Steven Chu},
  journal={Nature Nanotechnology},
  year={2019},
  volume={14},
  pages={420-425}
}
Electron microscopy has been instrumental in our understanding of complex biological systems. Although electron microscopy reveals cellular morphology with nanoscale resolution, it does not provide information on the location of different types of proteins. An electron-microscopy-based bioimaging technology capable of localizing individual proteins and resolving protein–protein interactions with respect to cellular ultrastructure would provide important insights into the molecular biology of a… Expand
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