Brief report: two-year outcome of a multidrug regimen in patients who did not respond to a protease inhibitor regimen.

@article{Youle2002BriefRT,
  title={Brief report: two-year outcome of a multidrug regimen in patients who did not respond to a protease inhibitor regimen.},
  author={Michael Youle and Mervyn Tyrer and Martin Fisher and Fiona Lampe and Deborah Wilson and Darren Ransom and Alister Story and Amanda Mocroft and Clive Loveday and Margaret A T Johnson and Andrew N Phillips},
  journal={Journal of acquired immune deficiency syndromes},
  year={2002},
  volume={29 1},
  pages={58-61}
}
In most studies, people who have not responded virologically to a protease inhibitor (PI)-containing regimen have tended to experience poor virologic responses to subsequent regimens. We describe the 2-year viral load, CD4 count, and clinical outcome of a multidrug regimen used in 60 people who had not responded virologically to a PI-containing regimen. At baseline, median CD4 count was 126/mm(3) (nadir 30/mm(3) ) and median viral load was 320,000 copies/mL. A median of five antiretroviral… CONTINUE READING

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