Brief report: Brain mechanisms in autism: Functional and structural abnormalities

  title={Brief report: Brain mechanisms in autism: Functional and structural abnormalities},
  author={Nancy J. Minshew},
  journal={Journal of Autism and Developmental Disorders},
  • N. Minshew
  • Published 1 April 1996
  • Biology, Psychology, Medicine
  • Journal of Autism and Developmental Disorders
The functional and structural abnormalities of the brain associated with autism have been completely redefined by research findings in the last decade, leading to new conceptualizations of the pathophysiology of this clinical syndrome. In addition, the investigation of the human genome and identification of spontaneous mutations in base pairs has for the first time provided a genetic model for sporadic disorders such as autism which do not follow classical Mendelian genetics but are nonetheless… 

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