Brief angiotensin converting enzyme inhibitor treatment in young spontaneously hypertensive rats reduces blood pressure long-term.

Abstract

Our study examines the long-term cardiovascular effects after a brief period of angiotensin converting enzyme (ACE) inhibitor treatment in young spontaneously hypertensive rats (SHR). SHR were treated with perindopril (3 mg/kg/day) by gavage from 2 to 6, from 6 to 10, or from 2 to 10 weeks of age. Systolic blood pressure was measured in the tail weekly… (More)

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@article{Harrap1990BriefAC, title={Brief angiotensin converting enzyme inhibitor treatment in young spontaneously hypertensive rats reduces blood pressure long-term.}, author={Stephen B. Harrap and Werner van der Merwe and S A Griffin and Fiona Macpherson and Alvin Lever}, journal={Hypertension}, year={1990}, volume={16 6}, pages={603-14} }