Brief Report: The Cochlear Microphonic as an Indication of Outer Hair Cell Function

  title={Brief Report: The Cochlear Microphonic as an Indication of Outer Hair Cell Function},
  author={Robert H. Withnell},
  journal={Ear and Hearing},
The extra-cellular cochlear microphonic is believed to be generated predominantly by outer hair cells and therefore it would seem reasonable to assume that the presence of a cochlear microphonic excludes outer hair cell dysfunction. Indeed, a diagnosis of auditory neuropathy might be, and has been, made on the basis of a cochlear microphonic present with an abnormal auditory brainstem response. Animal studies, however, have shown that the cochlear microphonic recorded from the round window is… 

Cochlear microphonic potential recorded by transtympanic electrocochleography in normally-hearing and hearing-impaired ears.

Long-lasting, high frequency cochlear microphonics with amplitudes comparable to those obtained from CNS- ears were found in auditory neuropathy patients, which could result from a variable combination of afferent compartment lesion, efferent system dysfacilitation and loss of outer hair cells.

Predicting the location of missing outer hair cells using the electrical signal recorded at the round window.

The electrical signal recorded at the round window was used to estimate the location of missing outer hair cells and the amplitude of the cochlear response was reduced for moderate signal levels with a limited effect at higher levels, indicating that the Cochlear Response was dominated by outer hair cell currents at high signal levels and neural potentials at low tomoderate signal levels.

An Electromechanical Model for the Cochlear Microphonic

A model is presented which can account for the generation of the cochlear microphonic signal, which is a nonlinear filtered version of the acoustic pressure at the tympanic membrane.

Identification of Different Subtypes of Auditory Neuropathy Using Electrocochleography

It is suggested that a presynaptic and postsynaptic type of auditory neuropathy exist, which may have implications for the design and use of cochlear implants.

Long Ringing Cochlear Microphonics - Not Unique to Auditory Neuropathy Spectrum Disorder in Children

The results show that abnormal CM detection in surface recording is not a distinctive feature of auditory neuropathy spectrum disorder and participants who are diagnosed with auditory neuropathic spectrum disorder based on traditional diagnostic criteria should be reviewed to rule out possible misdiagnosis.

Study of cochlear microphonic potentials in auditory neuropathy

Observations on mastoid versus ear canal recorded cochlear microphonic in newborns and adults.

Normative data collected in full-term newborns and adults with no known risk factors for cochlear or retrocochlear pathology suggest that the CM is easier to separate from stimulus artifact using an EC electrode and toneburst stimuli.

Frequency-Specific Electrocochleography Indicates that Presynaptic and Postsynaptic Mechanisms of Auditory Neuropathy Exist

Electrocochleography results suggest that a presynaptic and postsynaptic type of AN exist that may have implications for the fitting of cochlear implants.



Cochlear and Brain Stem Responses in Hearing Loss following Neonatal Hyperbilirubinemia

Functional evidence for auditory nerve damage in cases of hearing loss following neonatal hyperbilirubinemia while the hair cells are spared is provided.

Recording of the cochlear microphonic potential with surface electrodes.

The source along the basilar membrane of the cochlear microphonic potential recorded by surface electrodes in man.

An Introduction to the Physiology of Hearing

The book is written so that those entering auditory research from very little background in auditory neuroscience are able to understand the current research issues and research literature and is an excellent reading companion to practitioners and scholars.

The Auditory Periphery

The Auditory Periphery is written for hearing scientists, be they otolaryngologists, biophysicists, bioengineers, or physiologists.

Electrocochleography of ears with mumps deafness.

  • M. Sawada
  • Medicine, Biology
    Archives of otolaryngology
  • 1979
Electrocochleography was performed on 16 affected ears of 15 deaf patients whose deafness had resulted from the mumps. Although pure-tone audiometry showed no response in each case, the cases of

Elevation of auditory thresholds by spontaneous cochlear oscillations

It is demonstrated that high-intensity spontaneous otoacoustic emissions can vigorously activate auditory nerve fibres in mammals (Chinchilla laniger) and creates a 'Mine busy' signal that significantly degrades a neuron's ability to respond to sound and results in a hearing loss completely different from that caused by damage to sensory cells.

A computer simulation of the generation and distribution of cochlear potentials.

  • D. Strelioff
  • Biology
    The Journal of the Acoustical Society of America
  • 1973
An important finding was that, when the impedance of a hair cell was decreased, current from adjacent hair cells was shunted through it, thus providing a possible excitation‐inhibition mechanism for neural sharpening.

Some electrical circuit properties of the organ of Corti. I. Analysis without reactive elements