Brief Report: “Allergic Symptoms” in Children with Autism Spectrum Disorders. More than Meets the Eye?

@article{Angelidou2011BriefR,
  title={Brief Report: “Allergic Symptoms” in Children with Autism Spectrum Disorders. More than Meets the Eye?},
  author={Asimenia Angelidou and Konstantinos-Dionysios Alysandratos and Shahrzad Asadi and B. Zhang and Konstantinos Francis and Magdalini Vasiadi and Dimitrios C Kalogeromitros and Theoharis C. Theoharides},
  journal={Journal of Autism and Developmental Disorders},
  year={2011},
  volume={41},
  pages={1579-1585}
}
Many children with Autism Spectrum Disorders (ASD) have either family and/or personal history of “allergic symptomatology”, often in the absence of positive skin or RAST tests. These symptoms may suggest mast cell activation by non-allergic triggers. Moreover, children with mastocytosis or mast cell activation syndrome (MCAS), a spectrum of rare diseases characterized by increased number of activated mast cells in many organs, appear to have ASD at a rate tenfold higher (1/10 children) than… 
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He could fit in the palms of both hands, seemed to look at you beseechingly while you rushed to thread a vein and snake a tube down a tiny nostril of this 24 week preemie. Already exposed to the
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