Brief De.finitive Report a Role for Cd9 Molecules in T Cell Activation

  • Guang Tai, Yumi Yashiro, +7 authors H. Fujiwara
  • Published 1996


Costimulation mediated by the CD28 molecule plays an important role in optimal activation of T cells. However, CD28-deficient mice can mount effective T cell-dependent immune responses, suggesting the existence of other costimulatory systems. In a search for other costimulatory molecules on T cells, we have developed a monoclonal antibody (mAb) that can… (More)


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