Brief Communication: Tamoxifen Therapy for Nonmalignant Retroperitoneal Fibrosis

@article{vanBommel2006BriefCT,
  title={Brief Communication: Tamoxifen Therapy for Nonmalignant Retroperitoneal Fibrosis},
  author={Eric F.H. van Bommel and Tadek R. Hendriksz and A W Huiskes and A G Zeegers},
  journal={Annals of Internal Medicine},
  year={2006},
  volume={144},
  pages={101-106}
}
Context There are few effective treatments for retroperitoneal fibrosis. Contribution Of 19 adults with nonmalignant retroperitoneal fibrosis treated with tamoxifen for variable durations of time, 15 reported substantial resolution of symptoms and 14 had computed tomography scans that showed slow regression of retroperitoneal masses. Three men reported minor losses of libido, and 1 patient developed reversible hepatitis. Caution There was no control group in this small observational study… 

Tamoxifen Monotherapy in the Treatment of Retroperitoneal Fibrosis

TLDR
Tamoxifen is an alternative in the medical treatment of RPF, especially if patients want to avoid glucocorticoids and the potential of regression of fibrosis seems to be slightly inferior and the relapse rate is higher compared to steroids, but the rate of successful DJ removals is comparable.

Outcome in patients with idiopathic retroperitoneal fibrosis treated with corticosteroid or tamoxifen monotherapy

TLDR
CS are superior to TMX in treating iRPF disease, however, in patients with initial treatment success with primary treatment, recurrence rate was lower in TMX-treated patients.

Medical management of retroperitoneal fibrosis.

TLDR
Combined prednisone and mycophenolate mofetil appears to be an effective therapeutic option for patients with retroperitoneal fibrosis.

Long-term renal and patient outcome in idiopathic retroperitoneal fibrosis treated with prednisone.

TLDR
One-year treatment with prednisone is associated with a high rate of initial success, but a high recurrence rate, and despite frequent disease relapse, long-term renal and patient outcome was good.

Combined Prednisone and Mycophenolate Mofetil Treatment for Retroperitoneal Fibrosis

TLDR
Combined prednisone and mycophenolate mofetil therapy is a potentially effective treatment for retroperitoneal fibrosis that warrants evaluation in randomized trials.

Retroperitoneal fibrosis after chemo‐radiotherapy for cervical cancer: A case report

TLDR
The case of a 47‐year‐old woman who complained of lower abdominal pain 14 months after chemo‐radiotherapy for cervical cancer and was diagnosed with RPF caused by radiotherapy, which is doing well with no recurrence to date is reported.

Treatment of idiopathic retroperitoneal fibrosis with colchicine and steroids: a case series.

TLDR
Colchicine in association with a low induction dose of steroids produced remission rates in patients with IRPF similar to those for regimens using greater steroid doses alone or in combination with immunosuppressive drugs, and may have contributed to recurrence prevention.

Management of idiopathic retroperitoneal fibrosis from the urologist’s perspective

TLDR
The imaging procedures available today are unable to accurately differentiate between idiopathic and malignant RF and more clinical studies are needed in order standardize the protocol for diagnostic, treatment and follow up after medical or surgical management.
...

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TLDR
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TLDR
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TLDR
A case of idiopathic retroperitoneal fibrosis treated successfully with intra peritonealization of the ureters and sequential therapy with steroids and tamoxifen to minimize the side effects is presented.

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TLDR
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TLDR
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