Brief Communication: Sleep Curtailment in Healthy Young Men Is Associated with Decreased Leptin Levels, Elevated Ghrelin Levels, and Increased Hunger and Appetite

@article{Spiegel2004BriefCS,
  title={Brief Communication: Sleep Curtailment in Healthy Young Men Is Associated with Decreased Leptin Levels, Elevated Ghrelin Levels, and Increased Hunger and Appetite},
  author={Karine Spiegel and Esra Tasali and Plamen D. Penev and Eve Van Cauter},
  journal={Annals of Internal Medicine},
  year={2004},
  volume={141},
  pages={846-850}
}
Context Studies in animals and humans suggest that sleep duration is an important regulator of metabolism. Contribution In this study, 12 young, healthy, normal-weight men exhibited reductions in the satiety hormone leptin, increases in the hunger hormone ghrelin, and increases in hunger after 2 nights of only 4 hours of sleep compared with after 2 nights of 10 hours of sleep. Implications Inadequate sleep seems to influence the hormones that regulate satiety and hunger in a way that could… Expand

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