Bridging therapy and oral anticoagulation: current and future prospects.

@article{Spyropoulos2010BridgingTA,
  title={Bridging therapy and oral anticoagulation: current and future prospects.},
  author={Alex C. Spyropoulos},
  journal={Current opinion in hematology},
  year={2010},
  volume={17 5},
  pages={444-9}
}
PURPOSE OF REVIEW Patients undergoing oral anticoagulation treatment with vitamin K antagonist (VKA) therapy are at a high risk of bleeding when undergoing an invasive surgery or procedure. Bridging therapy with parenteral heparin, usually at therapeutic doses, aims to protect these patients against thromboembolism during temporary periprocedural interruption of VKA therapy. Whether or not to interrupt VKA therapy and initiate bridging therapy is a difficult decision that is based upon both the… CONTINUE READING