Bridging the gap: Membrane contact sites in signaling, metabolism, and organelle dynamics

@inproceedings{Prinz2014BridgingTG,
  title={Bridging the gap: Membrane contact sites in signaling, metabolism, and organelle dynamics},
  author={William A Prinz},
  booktitle={The Journal of cell biology},
  year={2014}
}
Regions of close apposition between two organelles, often referred to as membrane contact sites (MCSs), mostly form between the endoplasmic reticulum and a second organelle, although contacts between mitochondria and other organelles have also begun to be characterized. Although these contact sites have been noted since cells first began to be visualized with electron microscopy, the functions of most of these domains long remained unclear. The last few years have witnessed a dramatic increase… CONTINUE READING

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