## Implementing Optimal Designs for Dose–Response Studies Through Adaptive Randomization for a Small Population Group

- Yevgen Ryeznik, Oleksandr Sverdlov, Andrew C. Hooker
- The AAPS Journal
- 2018

Highly Influenced

@article{Kuznetsova2015BrickTR, title={Brick tunnel randomization and the momentum of the probability mass.}, author={Olga M Kuznetsova}, journal={Statistics in medicine}, year={2015}, volume={34 30}, pages={4031-56} }

- Published 2015 in Statistics in medicine
DOI:10.1002/sim.6601

The allocation space of an unequal-allocation permuted block randomization can be quite wide. The development of unequal-allocation procedures with a narrower allocation space, however, is complicated by the need to preserve the unconditional allocation ratio at every step (the allocation ratio preserving (ARP) property). When the allocation paths are depicted on the K-dimensional unitary grid, where allocation to the l-th treatment is represented by a step along the l-th axis, l = 1 to K, the… CONTINUE READING

Recent Discussions

This paper has been referenced on Twitter 3 times over the past 90 days. VIEW TWEETS

1 Citations

37 References

Similar Papers

Highly Influenced