Briarenolides K and L, New Anti-Inflammatory Briarane Diterpenoids from an Octocoral Briareum sp. (Briareidae)

@inproceedings{Su2015BriarenolidesKA,
  title={Briarenolides K and L, New Anti-Inflammatory Briarane Diterpenoids from an Octocoral Briareum sp. (Briareidae)},
  author={Yin-Di Su and Tzu-rong Su and Z F Wen and Tsong-Long Hwang and Lee-shing Fang and Jih-Jung Chen and Yang-Chang Wu and J H Sheu and Ping-Jyun Sung},
  booktitle={Marine drugs},
  year={2015}
}
Two new briarane-type diterpenoids, briarenolides K (1) and L (2), were isolated from an octocoral identified as Briareum sp. The structures of new briaranes 1 and 2 were elucidated by spectroscopic methods. In the in vitro anti-inflammatory effects test, briaranes 1 and 2 were found to significantly inhibit the accumulation of the pro-inflammatory iNOS protein of the lipopolysaccharide (LPS)-stimulated RAW264.7 macrophage cells. 
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