Brianodins A-D, briarane-type diterpenoids from soft coral Pachyclavularia sp.

@article{Ishiyama2008BrianodinsAB,
  title={Brianodins A-D, briarane-type diterpenoids from soft coral Pachyclavularia sp.},
  author={H. Ishiyama and Taro Okubo and Tetsuro Yasuda and Yohei Takahashi and K. Iguchi and J. Kobayashi},
  journal={Journal of natural products},
  year={2008},
  volume={71 4},
  pages={
          633-6
        }
}
Four new briarane-type diterpenoids, brianodins A-D ( 1- 4), were isolated from a soft coral, Pachyclavularia sp., and the structures and relative stereochemistry of 1- 4 were elucidated on the basis of spectroscopic data. The absolute configurations of 3 and 4 were assigned by the MTPA method. Brianodin A ( 1) showed a modest cytotoxicity. 
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