Brenner tumor of the testis: A case report and review of the literature.

  title={Brenner tumor of the testis: A case report and review of the literature.},
  author={Jing Quan and Lu Jin and Jia Hu and Tao He and Xiang Pan and Yu Ding and Jian Peng and Zhebo Chen and Shangqi Yang and Xiang-ming Mao and Yongqing Lai},
  journal={Molecular and clinical oncology},
  volume={6 1},
Brenner tumor is a rare type tumor, which mainly develops in the ovaries and rarely in the adnexal region and urinary system. To the best of our knowledge, only 5 cases of testicular Brenner tumor have been reported to date. In this report, we present the case of a 55-year-old patient who noted a swelling of the right scrotum for ~20 days. The clinical suspicion was an epididymal cyst. However, following surgical resection and subsequent pathological examination, the mass was diagnosed as a… Expand
4 Citations
Ovarian-type Tumors (Mullerian Tumors) of the Testis: Clinicopathologic Findings with Recent Advances
The clinical, morphologic, and immunohistochemical features of Mullerian-type epithelial tumors seen in the testis are described, with an emphasis on comparison with ovarian tumors. Expand
A peculiar case report of extraovarian Brenner tumor arising in the omentum
This is the first case of an extraovarian Brenner tumor arising in the omentum near the stomach ever reported in the English literature. Expand
Molecular and Clinical Insights in Malignant Brenner Tumor of the Testis With Liver Metastases:A Case Report
It is reported the first case of epididymal mBT with synchronous, multiple, liver metastases and a very dramatic clinical course and it is believed that the FGFR pathway could be an ideal candidate for personalized treatment, offering hope to a subset of patients with mBT. Expand
The mutational frequency of BRAF and KRAS in low‐grade serous testicular neoplasms—a case series
This study is to see if there are similar molecular abnormalities in these two tumours, low‐grade serous neoplasms of the testis and serous ovarian tumour, which are not fully established. Expand


Malignant Brenner tumor of the testis and epididymis.
This case appears to represent the first description of a malignant Brenner tumor of the testis and epididymis of the ovary, and displayed a component of transitional and squamous carcinoma that invaded the testicular parenchyma, epidIDymis, and vas deferens, and metastasized to periaortic lymph nodes. Expand
A brenner tumor of the testis
Based on histologic as well as embryologic studies, a hypothesis is made which reconciles advocates of origin of the Brenner tumor from germinal epithelium (müllerian) with proponents of origin in the rete complex (wolffian). Expand
Vaginal brenner tumor.
  • R. Shaco‐Levy, D. Benharroch
  • Medicine
  • International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • 2013
It is suggested that vaginal Brenner tumors arise from a metaplastic process within the mullerian epithelium. Expand
Polypoid Brenner tumor of the uterus.
The histogenesis of BT remains controversial; in this particular case the location of the BT suggests a mullerian origin, and the differential diagnosis included a pure transitional cell tumor, a mixed mullerians, and a uterine tumor resembling an ovarian sex cord tumor. Expand
Brenner tumor of the ovary: CT and MR findings.
Extensive amorphous calcification in a solid mass or solid component in a multilocular cystic mass is a characteristic finding of Brenner tumor of the ovary on CT and MRI. Expand
Paratesticular Brenner‐like tumor
The Wolffian‐mesonephric duct remnants ( appendage of epididymis) are accepted for its histogenesis, paralleling the theory of Berge and Borglin for Brenner tumors occurring in women. Expand
Brenner tumor of the uterus
A small tumor with histologic features of Brenner tumor within the wall of the uterus is described, and the possible histogenesis is briefly discussed. Expand
Mixed brenner and adenomatoid tumor of the testis. An ultrastructural study and histogenetic considerations
A previously unreported association of Brenner and adenomatoid tumor found in the tunica vaginalis testis is presented. Many ultrastructural features found in mesothelial cells such as intercellularExpand
Malignant Brenner Tumor of Ovary
Brenner tumor is a relatively uncommon neoplasm. It constitutes 1.4–2.5 % of all ovarian tumors and has a predilection for the postmenopausal women. Most Brenner tumors are benign, with only 2–5 %Expand
Intensive systemic chemotherapy is effective against recurrent malignant Brenner tumor of the ovary: An analysis of 10 cases within a single center.
The results showed that systemic chemotherapy is beneficial in patients with recurrence of a primary MBT of the ovary, especially in the locoregional recurrence. Expand