Bremazocine: a potent, long-acting opiate kappa-agonist.

@article{Rmer1980BremazocineAP,
  title={Bremazocine: a potent, long-acting opiate kappa-agonist.},
  author={D. R{\"o}mer and H. B{\"u}scher and R. C. Hill and R. Maurer and T. Petcher and H. Welle and H. C. Bakel and A. Akkerman},
  journal={Life sciences},
  year={1980},
  volume={27 11},
  pages={
          971-8
        }
}
Abstract The benzomorphan analogue bremazocine is a potent, centrally-acting analgesic with a long duration of action. In animal models it is free of physical and psychological dependence liability, produces no respiratory depression, and has a variety of other properties which justify its classification as a putative opiate kappa-receptor agonist. Binding studies with tritiated (−)-bremazocine on rat brain membrane preparations show that this molecule differs in its binding properties from… Expand
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