Brefeldin A does not inhibit the movement of phosphatidylethanolamine from its sites for synthesis to the cell surface.

@article{Vance1991BrefeldinAD,
  title={Brefeldin A does not inhibit the movement of phosphatidylethanolamine from its sites for synthesis to the cell surface.},
  author={Jean E. Vance and E J Aasman and R Szarka},
  journal={The Journal of biological chemistry},
  year={1991},
  volume={266 13},
  pages={8241-7}
}
Brefeldin A, a fungal metabolite which interrupts trafficking of proteins via the Golgi by causing disassembly of the Golgi stacks, has been used to investigate the mechanism of movement of phosphatidylethanolamine (PtdEtn) from its sites of synthesis to the cell surface. PtdEtn is made in hepatocytes by two major pathways, (a) from CDP-ethanolamine on the endoplasmic reticulum and (b) by decarboxylation of phosphatidylserine in mitochondria. Monolayer cultures of rat hepatocytes were incubated… CONTINUE READING

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