Breastmilk Is a Novel Source of Stem Cells with Multilineage Differentiation Potential

  title={Breastmilk Is a Novel Source of Stem Cells with Multilineage Differentiation Potential},
  author={Foteini Hassiotou and A. Salguero Beltran and Ellen M Chetwynd and Alison M Stuebe and Alecia-Jane Twigger and Philipp Metzger and Naomi J Trengove and Ching Tat Lai and Luis Filgueira and Pilar Blancafort and P. E. Hartmann},
  booktitle={Stem cells},
The mammary gland undergoes significant remodeling during pregnancy and lactation, which is fuelled by controlled mammary stem cell (MaSC) proliferation. The scarcity of human lactating breast tissue specimens and the low numbers and quiescent state of MaSCs in the resting breast have hindered understanding of both normal MaSC dynamics and the molecular determinants that drive their aberrant self-renewal in breast cancer. Here, we demonstrate that human breastmilk contains stem cells (hBSCs… CONTINUE READING
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Increasing CD 44 þ / CD 24  tumor stem cells and upregulation of COX - 2 and HDAC 6 , as major functions of HER 2 in breast cancer

  • KH Wang, AP Kao, CC Chang
  • Cell Res
  • 2012

Stem Cells 2012;5:39–56

  • J linked. Int
  • 2012

ways to the pluripotency network. Cell Res 2012;22:155–167

  • KH Wang, AP Kao, CC Chang
  • 2012

1038/onc.2011.656 [Epub Ahead of Print

  • AS Beltran, BT Richardson, X Yuan
  • 2011

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